oncobix

TOFPOMICS^® PLATFORM

TOFPOMICS^® PLATFORM, ONCOBIX'S unique library

R&D

TOFPOMICS^® PLATFORM Technology

ONCOBIX continues to discover the next-generation drug candidates with TOFPOMICS^® which is a platform with a unique library.

Causes of Diseases

- Our body's biological response is regulated by enzymes or proteins that act like a "switch" that turns it on and off.
- When the enzymes are damaged for various reasons, this switch remains on or off, which leads to diseases, such as cancer.

TOFPOMICS^® Technical Structure Diagram

- TOFPOMICS^® is a technology that finds compounds that fit the enzymes or protein binding site using a fragment library.
- The main mechanism is that analyze how to interact with the binding site and fragments and then link them to make even bigger molecules.
- This is a platform technology that synthesizes in-house, tests, and optimizes to generate the hit or lead compounds finally.

Fragment Library

Libraries at ONCOBIX
Validation of Binding Fragments

Synthesize after verifying bindable fragments suitable to problematic enzymes
In-house synthesis

Studies on generating the same compounds as the problematic synthetic enzymes.
Efficacy and toxicology evaluation

Efficacy and toxicology evaluation with a third-party evaluation to test for efficacy and toxicity.
Draw Candidate Compounds

TOFPOMICS^® Derived candidate compounds

Highlights of Our Unique Technology

With ONCOBIX's unique technology, there is no need for massive equipment such as NMR, SPR, or HTS.

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