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TOFPOMICS® PLATFORM

TOFPOMICS® PLATFORM, ONCOBIX'S unique library

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R&D

TOFPOMICS® PLATFORM Technology

ONCOBIX continues to discover the next-generation drug candidates with TOFPOMICS® which is a platform with a unique library.

Causes of Diseases

  • - Our body's biological response is regulated by enzymes or proteins that act like a "switch" that turns it on and off.
  • - When the enzymes are damaged for various reasons, this switch remains on or off, which leads to diseases, such as cancer.
  • 01
    Problems in Biotic Enzymes
  • 02
    Switch Remains On
  • 03
    Unregulated Proliferation of Cells
  • 04
    Causes Diseases including Cancer

TOFPOMICS® Technical Structure Diagram

  • - TOFPOMICS® is a technology that finds compounds that fit the enzymes or protein binding site using a fragment library.
  • - The main mechanism is that analyze how to interact with the binding site and fragments and then link them to make even bigger molecules.
  • - This is a platform technology that synthesizes in-house, tests, and optimizes to generate the hit or lead compounds finally.
  • Fragment Library

    Libraries at ONCOBIX
  • Validation of Binding Fragments

    Synthesize after verifying bindable fragments suitable to problematic enzymes
  • In-house synthesis

    Studies on generating the same compounds as the problematic synthetic enzymes.
  • Efficacy and toxicology evaluation

    Efficacy and toxicology evaluation with a third-party evaluation to test for efficacy and toxicity.
  • Draw Candidate Compounds

    TOFPOMICS® Derived candidate compounds

Highlights of Our Unique Technology

  • 01

    No need for large-sized equipment to apply existing technologies

  • 02

    Significantly saves time/cost with the unique technology

  • 03

    Can analyze targeted proteins

  • 04

    Synergy with a collaboration with the next-generation technology

With ONCOBIX's unique technology, there is no need for massive equipment such as NMR, SPR, or HTS.

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