oncobix

TOFPOMICS^® PLATFORM

TOFPOMICS^® PLATFORM, ONCOBIX'S unique library

R&D

TOFPOMICS^®

ONCOBIX continues to discover next-generation drug candidates with TOFPOMICS^®, an AI-powered platform technology that creates potential drug compounds in virtual space.

Causes of Diseases

- The human body's biological response is regulated by enzymes or proteins that act like a “switch.”
- When enzymes are damaged due to various reasons and this switch cannot function properly, it causes dysfunction in the cells which leads to diseases such as cancer.

01

Problems in Biotic Enzymes
02

Switch Remains On
03

Unregulated Proliferation of Cells
04

Causes Diseases including Cancer

TOFPOMICS^®

- Composed of OBAssistant, OBLibrary, and OBXpertise
- Drug structures are sourced from ONCOBIX’s accumulated library of refined target-oriented drug (fragmented) structures to target proteins identified by X-ray protein crystallography.
- Enables stable establishment of in-house pipeline development and intellectual property management.
- Combined with OpenAI^® / ChatGPT^® for greater speed and quality

Fragment Library

Libraries at ONCOBIX
Validation of Binding Fragments

Synthesize after verifying bindable fragments suitable to problematic enzymes
In-house synthesis

Studies on generating the same compounds as the problematic synthetic enzymes.
Efficacy and toxicology evaluation

Efficacy and toxicology evaluation with a third-party evaluation to test for efficacy and toxicity.
Draw Candidate Compounds

TOFPOMICS^® Derived candidate compounds

Highlights of Our Unique Technology

01

No need for large equipment
02

Significantly saves time/cost
03

Can analyze targeted proteins
04

Potential synergy with next-generation technology in future collaborations

With ONCOBIX's unique technology, there is no need for equipment such as NMR, SPR, or HTS.

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