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Other Pipelines

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PIPELINE

We are researching and developing a range of therapies.

ONCOBIX has pipelines for NSCLC treatment, pulmonary fibrosis treatment, and pancreatic/liver cancer treatments.

  • OBX10 Series

    비소세포폐암 치료제 아이콘

    Goals

    Develop supplements for the prevention and suppression of radiation-induced pulmonary fibrosis

    Current Stage : Lead Compound and MOA Exploration Stage

    - Research efficacy of ONCOBIX-owned compounds(in vivo, in vitro) - Examining the mechanism of action of ONCOBIX-owned compounds - Requires fibrosis pathogenesis target protein identification

    Future Plan

    - Hit compound discovery - MOA exploration and verification

  • OBX13 Series

    비소세포폐암 치료제 아이콘

    Goals

    Develop specific ALK/ROS1-positive NSCLC treatment

    Current Stage : Lead/candidate compound exploration stage

    - Document preparation for patent re-application - Efficacy studies in progress

    Future Plan

    - Patent re-application based on priority claims - Candidate compound for the first half decided, planned efficacy studies with the animal model

  • OBX09 Series

    비소세포폐암 치료제 아이콘

    Goals

    Develop FAK-targeted treatment for liver and pancreatic cancers

    Current Stage : Lead compound exploration stage

    - Initial compound delivery and evaluation completed - Drafting SAR, follow-up design suggested/span> - Initial evaluation result analysis, second delivery compound synthesis

    Future Plan

    - Hit compound discovery in the first half

MoA, mechanism of action; TPD, targeted protein degrader; SAR, structure-activity relationship

Ando K et al. Cancers 2020;12:942

Offringa R et al. Nat Rev Drug Discov 2022;21:821

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