Other Pipelines
PIPELINE
We are researching and developing a range of therapies.
ONCOBIX has pipelines for NSCLC treatment, pulmonary fibrosis treatment, and pancreatic/liver cancer treatments.
OBX10 Series
Goals
Develop supplements for the prevention and suppression of radiation-induced pulmonary fibrosis
Current Stage : Lead Compound and MOA Exploration Stage
- Research efficacy of ONCOBIX-owned compounds(in vivo, in vitro) - Examining the mechanism of action of ONCOBIX-owned compounds - Requires fibrosis pathogenesis target protein identification
Future Plan
- Hit compound discovery - MOA exploration and verification
OBX13 Series
Goals
Develop specific ALK/ROS1-positive NSCLC treatment
Current Stage : Lead/candidate compound exploration stage
- Document preparation for patent re-application - Efficacy studies in progress
Future Plan
- Patent re-application based on priority claims - Candidate compound for the first half decided, planned efficacy studies with the animal model
OBX09 Series
Goals
Develop FAK-targeted treatment for liver and pancreatic cancers
Current Stage : Lead compound exploration stage
- Initial compound delivery and evaluation completed - Drafting SAR, follow-up design suggested/span> - Initial evaluation result analysis, second delivery compound synthesis
Future Plan
- Hit compound discovery in the first half
MoA, mechanism of action; TPD, targeted protein degrader; SAR, structure-activity relationship
Ando K et al. Cancers 2020;12:942
Offringa R et al. Nat Rev Drug Discov 2022;21:821